MCEE

Across TCGA patient cohorts, MCEE protein abundance is significantly associated with the RNA expression of many other genes, with 15,317 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCEE-associated genes across cancer lineages are E2F7, CCNB2, and TUBB. Each is linked with MCEE in more than 7 cancer types. Because this analysis shows association rather than direction, both MCEE-to-partner and partner-to-MCEE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCEE versus E2F7 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCEE→partner) and Y-score (partner→MCEE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	E2F7 →	-0.850	-0.422	.001	<.001	3	8
BRCA	CCNB2 →	-0.928	-0.403	<.001	<.001	3	7
HNSC	TUBB →	-0.669	-0.368	.006	.007	3	7
BRCA	PRR11 →	-0.916	-0.444	<.001	<.001	3	7
COAD	GINS1 →	-0.943	-0.429	<.001	.001	3	6
GBM	LMNB1 →	-0.784	-0.294	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,317 associations by consensus.

MCEE vs E2F7 — OV

Explore this scatter interactively →