MC5R

Across TCGA cell cohorts, MC5R RNA expression is significantly associated with the RNA expression of many other genes, with 1,315 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MC5R-associated genes across cancer lineages are ANKRD30B, NCR3, and GUCY1A2. Each is linked with MC5R in more than 2 cancer types. Because this analysis shows association rather than direction, both MC5R-to-partner and partner-to-MC5R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MC5R versus ANKRD30B in BREAST, with a Pearson correlation of 0.44.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MC5R→partner) and Y-score (partner→MC5R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ANKRD30B →	+1.515	+0.123	<.001	<.001	3	2
LARGE_INTESTINE	NCR3 →	+0.094	+0.218	.003	<.001	3	2
BREAST	GUCY1A2 →	+1.053	+0.097	<.001	.001	3	2
BREAST	MMP16 →	+1.370	+0.128	<.001	<.001	3	2
BREAST	ATF5 →	+1.041	+0.094	.001	.006	3	2
LUNG_NSCLC_LUAD	SH2D5 →	+1.162	+0.289	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,315 associations by consensus.

MC5R vs ANKRD30B — BREAST

Explore this scatter interactively →