MBTD1

Across TCGA patient cohorts, MBTD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,366 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MBTD1-associated genes across cancer lineages are SPPL3, SNRPD3, and BLMH. Each is linked with MBTD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MBTD1-to-partner and partner-to-MBTD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBTD1 versus SPPL3 in GBM, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBTD1→partner) and Y-score (partner→MBTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPPL3 →	+0.624	+0.772	<.001	<.001	3	4
GBM	SNRPD3 →	+0.861	+0.727	<.001	<.001	3	3
LSCC	BLMH →	+0.584	+0.224	<.001	<.001	3	3
HNSC	PDCD2L →	+0.552	+0.462	.002	<.001	3	3
GBM	ILF3 →	+0.580	+0.490	.002	.001	3	3
HNSC	ERAL1 →	+0.688	+0.500	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,366 associations by consensus.

MBTD1 vs SPPL3 — GBM

Explore this scatter interactively →