Across TCGA patient cohorts, MBP protein abundance is significantly associated with the RNA expression of many other genes, with 9,708 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MBP-associated genes across cancer lineages are THEMIS, HLA-E, and KLRC4-KLRK1. Each is linked with MBP in more than 4 cancer types. Because this analysis shows association rather than direction, both MBP-to-partner and partner-to-MBP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBP→partner) and Y-score (partner→MBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	THEMIS →	+0.714	+0.248	<.001	<.001	3	5
BRCA	HLA-E →	+0.510	+0.480	<.001	<.001	3	5
LSCC	KLRC4-KLRK1 →	+0.338	+0.261	.003	.002	3	5
BRCA	TRBV7-9 →	+0.939	+0.420	<.001	<.001	3	5
LSCC	SAMSN1 →	+0.728	+0.307	<.001	<.001	3	5
HNSC	PATL2 →	+0.699	+0.648	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,708 associations by consensus.

Exploration

MBP survival (RNA) · tumor vs normal (RNA) · all MBP data types