MBOAT4

Across TCGA patient cohorts, MBOAT4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,256 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MBOAT4-associated proteins across cancer lineages are ELMO2, WIPF1, and PRMT3. Each is linked with MBOAT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBOAT4-to-partner and partner-to-MBOAT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBOAT4 versus ELMO2 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MBOAT4→partner) and Y-score (partner→MBOAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ELMO2 →	+0.216	+0.158	<.001	<.001	3	3
HNSC	WIPF1 →	+0.312	+0.371	.008	.001	3	3
LSCC	PRMT3 →	-0.294	-0.180	.003	.001	3	3
GBM	ARHGEF2 →	+0.312	+0.342	.002	<.001	3	3
PDAC	GCA →	-0.374	-0.457	.008	.003	3	3
COAD	MTERF3 →	-0.509	-0.163	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,256 associations by consensus.

MBOAT4 vs ELMO2 — LSCC

Explore this scatter interactively →