MBOAT2

Across TCGA patient cohorts, MBOAT2 mutation is significantly associated with the RNA expression of many other genes, with 3,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBOAT2-associated genes across cancer lineages are MIR7-3, MIR4774, and ZNF25-DT. Each is linked with MBOAT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBOAT2-to-partner and partner-to-MBOAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7-3 grouped by MBOAT2-low versus MBOAT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBOAT2→partner) and Y-score (partner→MBOAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7-3 →	+0.196	+1.809	.002	.009	3	3
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
UCEC	ZNF25-DT →	+0.120	+1.700	<.001	.001	3	2
UCEC	RNU6-1213P →	+0.133	+2.970	<.001	.001	3	2
BLCA	SNORD114-4 →	+0.440	+5.444	<.001	.002	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,331 associations by consensus.

MIR7-3 by MBOAT2 expression — UCEC

Explore this box plot interactively →