MBOAT1

Across TCGA pan-cancer cohorts, MBOAT1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MBOAT1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher MBOAT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MBOAT1 expression acts as an unfavorable survival marker.

GBM and PDAC are the cancer types where MBOAT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.410	0.930	.024	14	view →
PDAC	DFS	Tertile	All	0.277	0.608	.006	5	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MBOAT1–GBM (DFS)

Open the GBM breakdown →