MBL2

Across TCGA patient cohorts, MBL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,454 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MBL2-associated GO terms across cancer lineages are Positive regulation of myeloid cell differentiation, Cell junction disassembly, and Positive regulation of protein dephosphorylation. Each is linked with MBL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both MBL2-to-partner and partner-to-MBL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myeloid cell differentiation grouped by MBL2-low versus MBL2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBL2→partner) and Y-score (partner→MBL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of myeloid cell differentiation →	+0.049	+0.070	.001	.003	2	12
ESCA	Cell junction disassembly →	+0.076	+0.061	<.001	.003	3	10
STAD	Positive regulation of protein dephosphorylation →	+0.045	+0.035	<.001	.005	3	10
ESCA	Regulation of cell cycle G1/S phase transition →	+0.062	+0.062	<.001	.004	3	9
STAD	Regulation of binding →	+0.060	+0.074	<.001	<.001	2	10
GBM	Vascular endothelial growth factor receptor signaling pathway →	+0.054	+0.006	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,454 associations by consensus.

Positive regulation of myeloid cell differentiation by MBL2 expression — ESCA

Explore this box plot interactively →