MBL1P

Across TCGA pan-cancer cohorts, MBL1P Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MBL1P data layer compared with 26 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MBL1P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MBL1P expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ESCA, COAD, and CHOL are the cancer types where MBL1P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.285	0.691	.010	12	view →
COAD	DFS	Median	II,III,IV	0.140	0.756	.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
SKCM	OS	Median	II,III,IV	0.372	0.735	.049	3	view →
UCEC	DFS	Median	All	1.000	0.630	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MBL1P–ESCA (OS)

Open the ESCA breakdown →