MBL1P

Across TCGA patient cohorts, MBL1P mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBL1P-associated genes across cancer lineages are eEF2, eIF4E, and FoxM1. Each is linked with MBL1P in more than 1 cancer types. Because this analysis shows association rather than direction, both MBL1P-to-partner and partner-to-MBL1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by MBL1P-low versus MBL1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBL1P→partner) and Y-score (partner→MBL1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.454	+2.584	.006	.011	3	1
UCEC	eIF4E →	+0.259	+3.335	.008	.005	3	1
UCEC	FoxM1 →	+0.291	+2.584	.015	.011	3	1
UCEC	ACC1 →	+0.350	+2.820	.039	.035	3	1
UCEC	INPP4B →	-0.384	-3.169	.010	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.259	-3.687	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

eEF2 by MBL1P expression — UCEC

Explore this box plot interactively →