MBD3L5

Across TCGA patient cohorts, MBD3L5 RNA expression is significantly associated with the RNA expression of many other genes, with 5,874 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible MBD3L5-associated genes across cancer lineages are PRAMEF4, MBD3L2, and PRAMEF2. Each is linked with MBD3L5 in more than 13 cancer types. Because this analysis shows association rather than direction, both MBD3L5-to-partner and partner-to-MBD3L5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBD3L5 versus PRAMEF4 in SKCM, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L5→partner) and Y-score (partner→MBD3L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PRAMEF4 →	+0.762	+0.006	<.001	<.001	3	14
THYM	MBD3L2 →	+1.973	+0.101	<.001	<.001	3	13
SKCM	PRAMEF2 →	+1.121	+0.005	<.001	<.001	3	13
CESC	H3P21 →	+2.461	+0.056	<.001	<.001	3	12
THYM	MBD3L3 →	+1.398	+0.054	<.001	.002	3	12
THYM	MBD3L2B →	+1.024	+0.057	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,874 associations by consensus.

MBD3L5 vs PRAMEF4 — SKCM

Explore this scatter interactively →