MBD3L3

Across TCGA patient cohorts, MBD3L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,997 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MBD3L3-associated GO terms across cancer lineages are Ribosomal small subunit biogenesis, Pyrimidine nucleotide biosynthetic process, and Mitochondrial membrane organization. Each is linked with MBD3L3 in more than 7 cancer types. Because this analysis shows association rather than direction, both MBD3L3-to-partner and partner-to-MBD3L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit biogenesis grouped by MBD3L3-low versus MBD3L3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L3→partner) and Y-score (partner→MBD3L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribosomal small subunit biogenesis →	+0.163	+0.025	<.001	<.001	3	8
STAD	Pyrimidine nucleotide biosynthetic process →	+0.111	+0.027	<.001	<.001	3	7
STAD	Mitochondrial membrane organization →	+0.145	+0.027	<.001	<.001	3	7
STAD	Ribosomal large subunit biogenesis →	+0.158	+0.029	<.001	<.001	3	7
STAD	Carbohydrate biosynthetic process →	+0.090	+0.030	<.001	<.001	3	6
STAD	Formation of cytoplasmic translation initiation complex →	+0.148	+0.025	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,997 associations by consensus.

Ribosomal small subunit biogenesis by MBD3L3 expression — STAD

Explore this box plot interactively →