Across TCGA cell cohorts, MBD3L2B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,234 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MBD3L2B-associated GO terms across cancer lineages are Protein-RNA complex assembly, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, and mRNA splicing, via spliceosome. Each is linked with MBD3L2B in more than 3 cancer types. Because this analysis shows association rather than direction, both MBD3L2B-to-partner and partner-to-MBD3L2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L2B→partner) and Y-score (partner→MBD3L2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein-RNA complex assembly →	+0.094	+1.821	<.001	<.001	3	4
BONE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.047	+1.158	.005	.001	3	4
BONE	mRNA splicing, via spliceosome →	+0.047	+1.158	.005	.001	3	4
BONE	Positive regulation of DNA damage checkpoint →	+0.091	+1.170	.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal protein catabolic process →	+0.048	+0.051	.002	.002	3	3
UPPER_AERODIGESTIVE_TRACT	Striated muscle contraction →	+0.039	+0.049	.009	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,234 associations by consensus.

Exploration

MBD3L2B survival (RNA) · tumor vs normal (RNA) · all MBD3L2B data types