Across TCGA pan-cancer cohorts, MBD3L2B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MBD3L2B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MBD3L2B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MBD3L2B is over-expressed in tumor.

KIRP and KIRC are the cancer types where MBD3L2B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MBD3L2B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.022	.037	3	view →
KIRC	All	All	+0.009	.016	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MBD3L2B RNA expression & survival · all MBD3L2B data types