MBD3L2

Across TCGA patient cohorts, MBD3L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,218 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MBD3L2-associated GO terms across cancer lineages are Mitochondrial transport, Mitochondrial membrane organization, and Protein localization to mitochondrion. Each is linked with MBD3L2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MBD3L2-to-partner and partner-to-MBD3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial transport grouped by MBD3L2-low versus MBD3L2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L2→partner) and Y-score (partner→MBD3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial transport →	+0.092	+0.042	<.001	.005	3	6
STAD	Mitochondrial membrane organization →	+0.094	+0.046	<.001	<.001	3	6
STAD	Protein localization to mitochondrion →	+0.090	+0.043	<.001	<.001	3	5
STAD	Establishment of protein localization to mitochondrial membrane →	+0.089	+0.038	<.001	<.001	3	5
STAD	Mitotic spindle assembly →	+0.095	+0.053	<.001	<.001	3	5
STAD	Nucleoside phosphate biosynthetic process →	+0.084	+0.049	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,218 associations by consensus.

Mitochondrial transport by MBD3L2 expression — STAD

Explore this box plot interactively →