MBD3L2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MBD3L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 831 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MBD3L2-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Mineralocorticoid biosynthetic process, and Body morphogenesis. Each is linked with MBD3L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBD3L2-to-partner and partner-to-MBD3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by MBD3L2-low versus MBD3L2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L2→partner) and Y-score (partner→MBD3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEEstablishment of epithelial cell apical/basal polarity →-0.082-0.389.006.00932
BONEMineralocorticoid biosynthetic process →+1.261+1.770.004.00732
SOFT_TISSUEBody morphogenesis →+0.077+0.396<.001.00332
SOFT_TISSUENegative regulation of transcription initiation-coupled chromatin remodeling →+0.119+0.536.004.00532
BONEPositive regulation of sodium ion transmembrane transport →-0.243-1.568<.001.00332
BONETertiary alcohol biosynthetic process →+1.051+1.289.006.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 831 associations by consensus.

Establishment of epithelial cell apical/basal polarity by MBD3L2 expression — SOFT_TISSUE

Box plot of Establishment of epithelial cell apical/basal polarity in MBD3L2-low vs MBD3L2-high samples in SOFT_TISSUE.

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Exploration