MBD3L1

Across TCGA patient cohorts, MBD3L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,844 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MBD3L1-associated GO terms across cancer lineages are tRNA metabolic process, Peptidyl-lysine acetylation, and Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with MBD3L1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MBD3L1-to-partner and partner-to-MBD3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by MBD3L1-low versus MBD3L1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L1→partner) and Y-score (partner→MBD3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA metabolic process →	+0.061	+0.159	<.001	<.001	3	15
STAD	Peptidyl-lysine acetylation →	+0.057	+0.146	<.001	<.001	3	15
STAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.052	+0.128	<.001	<.001	3	14
STAD	Regulation of DNA repair →	+0.060	+0.145	<.001	<.001	3	14
STAD	Positive regulation of transcription by RNA polymerase I →	+0.068	+0.135	<.001	<.001	3	14
STAD	Telomere organization →	+0.060	+0.141	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,844 associations by consensus.

tRNA metabolic process by MBD3L1 expression — STAD

Explore this box plot interactively →