MBD3L1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MBD3L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 192 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MBD3L1-associated GO terms across cancer lineages are Negative regulation of bone mineralization involved in bone maturation, Regulation of hippocampal neuron apoptotic process, and Negative regulation of hippocampal neuron apoptotic process. Each is linked with MBD3L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBD3L1-to-partner and partner-to-MBD3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of bone mineralization involved in bone maturation grouped by MBD3L1-low versus MBD3L1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L1→partner) and Y-score (partner→MBD3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYNegative regulation of bone mineralization involved in bone maturation →-1.423-0.045<.001.00533
OVARYRegulation of hippocampal neuron apoptotic process →+1.165+0.045.001.00532
OVARYNegative regulation of hippocampal neuron apoptotic process →+1.088+0.045.001.00532
OVARYSerotonin secretion →+1.369+0.082<.001.00432
OVARYSerotonin production involved in inflammatory response →+1.369+0.082<.001.00432
OVARYSerotonin secretion involved in inflammatory response →+1.369+0.082<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

Negative regulation of bone mineralization involved in bone maturation by MBD3L1 expression — OVARY

Box plot of Negative regulation of bone mineralization involved in bone maturation in MBD3L1-low vs MBD3L1-high samples in OVARY.

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Exploration