MBD2

Across TCGA cell cohorts, MBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,323 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MBD2-associated GO terms across cancer lineages are Cellular response to monoamine stimulus, Ventricular cardiac muscle tissue development, and Left ventricular cardiac muscle tissue morphogenesis. Each is linked with MBD2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MBD2-to-partner and partner-to-MBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to monoamine stimulus grouped by MBD2-low versus MBD2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD2→partner) and Y-score (partner→MBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cellular response to monoamine stimulus →	+0.075	+0.656	<.001	<.001	3	11
SOFT_TISSUE	Ventricular cardiac muscle tissue development →	+0.104	+0.861	<.001	<.001	3	11
LARGE_INTESTINE	Left ventricular cardiac muscle tissue morphogenesis →	+0.778	+1.031	<.001	<.001	3	10
BONE	mRNA alternative polyadenylation →	+0.079	+0.868	<.001	.001	3	9
SOFT_TISSUE	Response to dehydroepiandrosterone →	+0.156	+0.750	.004	.005	3	9
LARGE_INTESTINE	Maternal behavior →	+0.307	+0.882	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,323 associations by consensus.

Cellular response to monoamine stimulus by MBD2 expression — OVARY

Explore this box plot interactively →