MB21D2

Across TCGA patient cohorts, MB21D2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,292 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MB21D2-associated genes across cancer lineages are MEIS3, TNFAIP6, and ANGPTL2. Each is linked with MB21D2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MB21D2-to-partner and partner-to-MB21D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MB21D2 versus MEIS3 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MB21D2→partner) and Y-score (partner→MB21D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEIS3 →	+0.935	+0.350	<.001	<.001	3	5
PDAC	TNFAIP6 →	+1.080	+0.349	<.001	<.001	3	5
CCRCC	ANGPTL2 →	+0.640	+0.213	.001	.002	2	6
BRCA	LATS2 →	+0.448	+0.232	.001	.004	3	5
LUAD	ADAMTS12 →	+0.726	+0.260	.001	<.001	3	5
UCEC	TPM4 →	+0.681	+0.546	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,292 associations by consensus.

MB21D2 vs MEIS3 — GBM

Explore this scatter interactively →