MB21D2

Across TCGA cell cohorts, MB21D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,086 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MB21D2-associated GO terms across cancer lineages are Regulation of heart rate by chemical signal, Regulation of protein ubiquitination, and Peptidyl-glycine modification. Each is linked with MB21D2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MB21D2-to-partner and partner-to-MB21D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heart rate by chemical signal grouped by MB21D2-low versus MB21D2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MB21D2→partner) and Y-score (partner→MB21D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of heart rate by chemical signal →	+0.408	+0.988	<.001	<.001	3	10
OVARY	Regulation of protein ubiquitination →	+0.071	+1.252	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Peptidyl-glycine modification →	+0.218	+1.384	<.001	<.001	3	10
KIDNEY	Positive regulation of extrinsic apoptotic signaling pathway →	+0.111	+1.915	.001	.002	3	10
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.059	+0.978	.001	.004	2	11
KIDNEY	Myofibril assembly →	+0.266	+2.124	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,086 associations by consensus.

Regulation of heart rate by chemical signal by MB21D2 expression — BONE

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