MAZ

Across TCGA patient cohorts, MAZ protein abundance is significantly associated with the RNA expression of many other genes, with 14,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAZ-associated genes across cancer lineages are ZNF785, SGF29, and LUC7L. Each is linked with MAZ in more than 6 cancer types. Because this analysis shows association rather than direction, both MAZ-to-partner and partner-to-MAZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAZ versus ZNF785 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAZ→partner) and Y-score (partner→MAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF785 →	+0.781	+0.417	<.001	<.001	3	7
OV	SGF29 →	+0.496	+0.377	.004	.008	3	6
OV	LUC7L →	+0.608	+0.383	.005	.006	3	6
BRCA	COQ7 →	+0.744	+0.338	<.001	.002	3	6
BRCA	NFATC2IP →	+0.402	+0.306	<.001	<.001	3	6
HNSC	TFAP4 →	+0.582	+0.391	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,222 associations by consensus.

MAZ vs ZNF785 — BRCA

Explore this scatter interactively →