MAZ

Across TCGA cell cohorts, MAZ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,163 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAZ-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Cell cycle phase transition, and DNA strand elongation involved in DNA replication. Each is linked with MAZ in more than 16 cancer types. Because this analysis shows association rather than direction, both MAZ-to-partner and partner-to-MAZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by MAZ-low versus MAZ-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAZ→partner) and Y-score (partner→MAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.088	+0.953	.002	.001	3	17
BONE	Cell cycle phase transition →	+0.101	+1.103	.003	.002	3	14
BONE	DNA strand elongation involved in DNA replication →	+0.217	+1.138	<.001	<.001	3	14
BONE	Transcription initiation-coupled chromatin remodeling →	+0.088	+0.916	<.001	.005	3	14
LUNG_SCLC	Regulation of chromatin organization →	+0.118	+0.645	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.071	+1.120	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,163 associations by consensus.

Regulation of nucleotide-excision repair by MAZ expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →