MAZ

Across TCGA cell cohorts, MAZ mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAZ-associated genes across cancer lineages are KRTAP19-3, KRTAP10-1, and AVP. Each is linked with MAZ in more than 1 cancer types. Because this analysis shows association rather than direction, both MAZ-to-partner and partner-to-MAZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-3 grouped by MAZ-low versus MAZ-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAZ→partner) and Y-score (partner→MAZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRTAP19-3 →	+0.236	+4.807	<.001	.006	3	1
BREAST	KRTAP10-1 →	+0.012	+5.169	<.001	.005	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	1
BLOOD_Leukemia	GH2 →	+0.014	+3.969	<.001	.009	3	1
BLOOD_Leukemia	BTBD16 →	+0.090	+3.696	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

KRTAP19-3 by MAZ expression — BLOOD_Myeloma

Explore this box plot interactively →