MAX

Across TCGA cell cohorts, MAX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,284 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAX-associated GO terms across cancer lineages are Protein farnesylation, Regulation of autophagosome maturation, and Positive regulation of GTPase activity. Each is linked with MAX in more than 11 cancer types. Because this analysis shows association rather than direction, both MAX-to-partner and partner-to-MAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein farnesylation grouped by MAX-low versus MAX-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAX→partner) and Y-score (partner→MAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein farnesylation →	+0.111	+0.794	<.001	<.001	3	12
PANCREAS	Regulation of autophagosome maturation →	+0.080	+0.715	<.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of GTPase activity →	+0.047	+0.498	.001	.001	3	10
OVARY	Positive regulation of TORC2 signaling →	+0.088	+0.918	.001	<.001	3	10
SOFT_TISSUE	Regulation of cellular response to transforming growth factor beta stimulus →	+0.045	+0.747	.008	.002	3	9
LARGE_INTESTINE	Autophagosome organization →	+0.050	+0.442	.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,284 associations by consensus.

Protein farnesylation by MAX expression — UPPER_AERODIGESTIVE_TRACT

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