MAST4-AS1

Across TCGA pan-cancer cohorts, MAST4-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated MAST4-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MAST4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAST4-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LUSC show a favorable association.

ACC, UVM, and LUSC are the cancer types where MAST4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.393	0.863	<.001	103	view →
UVM	OS	Tertile	All	0.826	0.425	<.001	82	view →
LUSC	OS	Tertile	All	0.756	0.598	<.001	62	view →
UCEC	OS	Median	All	0.915	0.832	.001	60	view →
STAD	OS	Median	IV	0.642	0.194	.003	57	view →
UCS	OS	Median	IV	0.224	0.732	.018	36	view →
KIRP	OS	Median	III,IV	0.312	0.638	.014	33	view →
MESO	OS	Median	IV	0.809	0.310	.004	33	view →
CESC	DFS	Tertile	All	0.876	0.764	.008	32	view →
SKCM	OS	Quartile	II,III,IV	0.732	0.917	.004	22	view →
LIHC	DFS	Median	All	0.547	0.336	.001	15	view →
KICH	DFS	Quartile	II,III,IV	0.513	0.896	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

MAST4-AS1–ACC (OS)

Open the ACC breakdown →