Across TCGA cell cohorts, MAS1L mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAS1L-associated genes across cancer lineages are SLC22A9, LCE5A, and KRTAP19-2. Each is linked with MAS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both MAS1L-to-partner and partner-to-MAS1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAS1L→partner) and Y-score (partner→MAS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SLC22A9 →	+0.202	+4.044	<.001	.009	3	1
LUNG_SCLC	LCE5A →	+0.637	+4.269	<.001	.005	3	1
LUNG_SCLC	KRTAP19-2 →	+0.127	+4.643	<.001	.004	3	1
LUNG_SCLC	DAZ3 →	+1.336	+4.044	<.001	.009	3	1
BLOOD_Lymphoma	PRLHR →	+0.006	+4.247	<.001	.004	3	1
BLOOD_Lymphoma	IL9 →	+2.422	+3.321	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

MAS1L survival (RNA) · tumor vs normal (RNA) · all MAS1L data types