MARVELD2

Across TCGA patient cohorts, MARVELD2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,506 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MARVELD2-associated genes across cancer lineages are CYP1B1, OCLN, and MAP7D3. Each is linked with MARVELD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MARVELD2-to-partner and partner-to-MARVELD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARVELD2 versus CYP1B1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARVELD2→partner) and Y-score (partner→MARVELD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYP1B1 →	-1.173	-0.527	<.001	<.001	3	5
HNSC	OCLN →	+1.410	+0.422	<.001	.009	3	5
BRCA	MAP7D3 →	-0.770	-0.463	<.001	<.001	3	4
COAD	GLS →	-0.710	-0.394	.009	.002	3	4
BRCA	DOK5 →	-0.685	-0.386	<.001	<.001	2	5
LSCC	TSPAN2 →	-0.895	-0.415	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,506 associations by consensus.

MARVELD2 vs CYP1B1 — UCEC

Explore this scatter interactively →