MARVELD2

Across TCGA patient cohorts, MARVELD2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MARVELD2-associated genes across cancer lineages are CLP, Erythrocytes, and Macrophages M2. Each is linked with MARVELD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARVELD2-to-partner and partner-to-MARVELD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by MARVELD2-low versus MARVELD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARVELD2→partner) and Y-score (partner→MARVELD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.062	-2.072	.024	.019	3	1
UCEC	Erythrocytes →	+0.031	+2.807	.004	.003	3	1
UCEC	Macrophages M2 →	+0.011	+1.703	.018	.039	3	1
UCEC	MEP →	+0.033	+2.126	.005	.011	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CLP by MARVELD2 expression — UCEC

Explore this box plot interactively →