MARVELD2

Across TCGA cell cohorts, MARVELD2 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MARVELD2-associated genes across cancer lineages are LUZP4, IFNG, and IL4. Each is linked with MARVELD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARVELD2-to-partner and partner-to-MARVELD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LUZP4 grouped by MARVELD2-low versus MARVELD2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARVELD2→partner) and Y-score (partner→MARVELD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LUZP4 →	+0.379	+3.475	<.001	.006	3	1
BLOOD_Leukemia	IFNG →	+0.147	+3.567	<.001	.003	3	1
BLOOD_Leukemia	IL4 →	+1.813	+4.007	<.001	.002	3	1
BLOOD_Leukemia	HRG →	+0.308	+4.177	<.001	.001	3	1
BLOOD_Leukemia	ATXN3L →	+0.320	+3.684	<.001	.004	3	1
BLOOD_Leukemia	DPP6 →	+0.437	+3.623	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

LUZP4 by MARVELD2 expression — BLOOD_Leukemia

Explore this box plot interactively →