MARS1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MARS1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,550 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MARS1-associated genes across cancer lineages are EEF1E1, GYPC, and FLI1. Each is linked with MARS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MARS1-to-partner and partner-to-MARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARS1 versus EEF1E1 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARS1→partner) and Y-score (partner→MARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVEEF1E1 →+0.745+0.315<.001.00138
COADGYPC →-0.727-0.199<.001<.00136
HNSCFLI1 →-0.688-0.167<.001.00136
OVSLA →-0.950-0.252<.001.00536
OVCXCL12 →-1.459-0.294.001.00126
LUADVSIR →-0.643-0.270<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,550 associations by consensus.

MARS1 vs EEF1E1 — OV

Per-sample scatter of MARS1 vs EEF1E1 in OV (Pearson r = 0.45).

Explore this scatter interactively →

Exploration