MARCKSL1

Across TCGA cell cohorts, MARCKSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,322 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MARCKSL1-associated GO terms across cancer lineages are Regulation of glucose mediated signaling pathway, Positive regulation of glucose mediated signaling pathway, and Receptor-mediated endocytosis of virus by host cell. Each is linked with MARCKSL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MARCKSL1-to-partner and partner-to-MARCKSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glucose mediated signaling pathway grouped by MARCKSL1-low versus MARCKSL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCKSL1→partner) and Y-score (partner→MARCKSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of glucose mediated signaling pathway →	+0.129	+2.984	<.001	<.001	3	11
BONE	Positive regulation of glucose mediated signaling pathway →	+0.129	+2.984	<.001	<.001	3	11
LUNG_SCLC	Receptor-mediated endocytosis of virus by host cell →	-0.198	-1.529	<.001	<.001	3	11
STOMACH	Stress response to copper ion →	-0.379	-1.837	<.001	<.001	3	11
BREAST	Regulation of myoblast differentiation →	+0.084	+0.969	<.001	.004	3	11
STOMACH	Detoxification of copper ion →	-0.379	-1.837	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,322 associations by consensus.

Regulation of glucose mediated signaling pathway by MARCKSL1 expression — BONE

Explore this box plot interactively →