MARCHF6

Across TCGA patient cohorts, MARCHF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,952 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MARCHF6-associated proteins across cancer lineages are WDR70, WRNIP1, and ZFR. Each is linked with MARCHF6 in more than 4 cancer types. Because this analysis shows association rather than direction, both MARCHF6-to-partner and partner-to-MARCHF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARCHF6 versus WDR70 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF6→partner) and Y-score (partner→MARCHF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR70 →	+0.394	+0.513	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.494	+0.601	<.001	<.001	3	5
HNSC	ZFR →	+0.265	+0.752	<.001	<.001	3	5
HNSC	NSUN2 →	+0.454	+0.952	<.001	<.001	3	5
LSCC	SMC3 →	+0.291	+0.503	<.001	<.001	3	5
LSCC	SSB →	+0.233	+0.520	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,952 associations by consensus.

MARCHF6 vs WDR70 — LSCC

Explore this scatter interactively →