Across TCGA cell cohorts, MARCHF5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,596 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MARCHF5-associated genes across cancer lineages are MAN2B2, UBC, and CAMK2N1. Each is linked with MARCHF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both MARCHF5-to-partner and partner-to-MARCHF5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF5→partner) and Y-score (partner→MARCHF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	MAN2B2 →	-1.242	-0.651	.001	.004	3	7
CNS	UBC →	-0.857	-0.842	.002	<.001	3	7
CNS	CAMK2N1 →	-2.632	-0.962	.001	<.001	3	7
PANCREAS	CAD →	+0.959	+0.882	.003	.002	3	7
SKIN	SARAF →	-0.814	-0.811	.005	.001	3	6
OESOPHAGUS	ADAM9 →	-1.041	-0.661	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,596 associations by consensus.

Exploration

MARCHF5 survival (RNA) · tumor vs normal (RNA) · all MARCHF5 data types