Across TCGA patient cohorts, MARCHF11 mutation is significantly associated with the RNA expression of many other genes, with 475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MARCHF11-associated genes across cancer lineages are SMIM10L2A, SNRPGP7, and LINC00900. Each is linked with MARCHF11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MARCHF11-to-partner and partner-to-MARCHF11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF11→partner) and Y-score (partner→MARCHF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SMIM10L2A →	-0.718	-3.575	.001	.002	3	3
COAD	SNRPGP7 →	+1.025	+5.602	<.001	.004	3	3
SKCM	LINC00900 →	-0.682	-3.163	<.001	<.001	3	2
UCEC	RAD51 →	+0.696	+2.425	.001	.002	3	2
READ	MTCO3P39 →	+0.114	+5.039	<.001	.008	3	2
SKCM	MTND6P2 →	+0.062	+2.240	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 475 associations by consensus.

Exploration

MARCHF11 survival (RNA) · tumor vs normal (RNA) · all MARCHF11 data types