Across TCGA cell cohorts, MARCHF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 778 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MARCHF11-associated GO terms across cancer lineages are Protein transmembrane transport, Adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Glyceraldehyde-3-phosphate biosynthetic process. Each is linked with MARCHF11 in more than 3 cancer types. Because this analysis shows association rather than direction, both MARCHF11-to-partner and partner-to-MARCHF11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF11→partner) and Y-score (partner→MARCHF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein transmembrane transport →	+0.056	+2.490	.006	.002	3	3
LUNG_SCLC	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.058	-2.983	.001	<.001	3	3
BLOOD_Lymphoma	Glyceraldehyde-3-phosphate biosynthetic process →	+0.055	+0.107	<.001	.001	3	3
LUNG_SCLC	Macroautophagy →	+0.042	+2.593	.001	.001	3	3
LUNG_SCLC	Positive regulation of mitophagy →	+0.087	+2.090	.003	.009	3	3
LUNG_SCLC	Positive regulation of autophagy of mitochondrion →	+0.084	+2.366	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

Exploration

MARCHF11 survival (RNA) · tumor vs normal (RNA) · all MARCHF11 data types