MARCHF10-DT

Across TCGA pan-cancer cohorts, MARCHF10-DT RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MARCHF10-DT’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where MARCHF10-DT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MARCHF10-DT is over-expressed in tumor.

ESCA and KIRC are the cancer types where MARCHF10-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MARCHF10-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.035	.019	2	view →
KIRC	All	III,IV	+0.010	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MARCHF10-DT–ESCA

Open the ESCA breakdown →