MAPKAPK5-AS1

Across TCGA pan-cancer cohorts, MAPKAPK5-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated MAPKAPK5-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MAPKAPK5-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAPKAPK5-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and CESC show a favorable association.

KICH, LIHC, and MESO are the cancer types where MAPKAPK5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.668	1.000	.002	81	view →
LIHC	OS	Median	All	0.572	0.794	<.001	81	view →
MESO	DFS	Quartile	All	0.252	0.504	.003	55	view →
KIRC	DFS	Tertile	IV	0.345	0.763	<.001	54	view →
ACC	DFS	Median	All	0.249	0.666	<.001	31	view →
UCS	OS	Quartile	All	0.842	0.571	.016	30	view →
LUAD	DFS	Quartile	All	0.350	0.573	.005	26	view →
UVM	DFS	Tertile	III,IV	0.099	1.000	.004	25	view →
CESC	OS	Median	All	0.916	0.830	.005	24	view →
BRCA	OS	Tertile	III,IV	0.956	0.844	.004	24	view →
UCEC	DFS	Median	III,IV	0.857	0.739	.002	22	view →
PRAD	DFS	Quartile	All	0.732	0.927	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

MAPKAPK5-AS1–KICH (OS)

Open the KICH breakdown →