MAPKAPK3

Across TCGA patient cohorts, MAPKAPK3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,783 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPKAPK3-associated genes across cancer lineages are IFI30, PELATON, and PLEK. Each is linked with MAPKAPK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAPKAPK3-to-partner and partner-to-MAPKAPK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPKAPK3 versus IFI30 in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPKAPK3→partner) and Y-score (partner→MAPKAPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IFI30 →	+0.768	+0.358	<.001	<.001	3	7
GBM	PELATON →	+0.656	+0.349	<.001	<.001	3	7
UCEC	PLEK →	+1.297	+0.392	<.001	<.001	3	6
GBM	NCF2 →	+0.849	+0.285	<.001	<.001	3	6
LSCC	CCRL2 →	+0.737	+0.277	<.001	<.001	3	6
GBM	LILRB2 →	+0.890	+0.324	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,783 associations by consensus.

MAPKAPK3 vs IFI30 — GBM

Explore this scatter interactively →