MAPK8IP3

Across TCGA patient cohorts, MAPK8IP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,869 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPK8IP3-associated proteins across cancer lineages are RPL6, MAPK8IP3_S365, and PDPK1. Each is linked with MAPK8IP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAPK8IP3-to-partner and partner-to-MAPK8IP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPK8IP3 versus RPL6 in GBM, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK8IP3→partner) and Y-score (partner→MAPK8IP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL6 →	-0.464	-0.340	<.001	<.001	3	4
LSCC	MAPK8IP3_S365 →	+0.949	+0.455	.005	.003	3	4
BRCA	PDPK1 →	+0.229	+0.631	<.001	.006	3	4
PDAC	SLC39A14 →	-0.518	-0.436	<.001	<.001	3	3
GBM	MAPRE3 →	+0.440	+0.323	<.001	<.001	3	3
BRCA	METTL26 →	+0.290	+0.502	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,869 associations by consensus.

MAPK8IP3 vs RPL6 — GBM

Explore this scatter interactively →