MAPK8IP2

Across TCGA patient cohorts, MAPK8IP2 mutation is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAPK8IP2-associated genes across cancer lineages are MIR3913-1, SIGLEC27P, and MIR516A1. Each is linked with MAPK8IP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAPK8IP2-to-partner and partner-to-MAPK8IP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3913-1 grouped by MAPK8IP2-low versus MAPK8IP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK8IP2→partner) and Y-score (partner→MAPK8IP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR3913-1 →	+0.380	+4.497	<.001	.009	3	3
BLCA	SIGLEC27P →	+0.211	+5.444	<.001	.002	3	3
LUSC	MIR516A1 →	+0.883	+7.924	<.001	.008	3	2
LUSC	MIR517C →	+0.316	+7.924	<.001	.008	3	2
LUAD	RNU6-1040P →	+0.497	+7.930	<.001	.008	3	2
LUAD	RNU6-982P →	+1.021	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

MIR3913-1 by MAPK8IP2 expression — BLCA

Explore this box plot interactively →