MAPK15

Across TCGA pan-cancer cohorts, MAPK15 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MAPK15’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MAPK15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAPK15 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

COAD, KICH, and STAD are the cancer types where MAPK15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAPK15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+3.278	<.001	12	view →
KICH	Female	II,III,IV	−2.865	<.001	11	view →
STAD	All	II,III,IV	+1.649	<.001	9	view →
KIRC	Female	All	+0.997	<.001	9	view →
BLCA	Male	III,IV	+2.084	<.001	8	view →
BRCA	All	II,III,IV	+1.207	<.001	6	view →
CHOL	Female	All	+4.633	<.001	5	view →
READ	All	All	+2.280	<.001	5	view →
HNSC	Male	All	+0.520	.005	5	view →
LUSC	All	All	−0.895	<.001	4	view →
LUAD	All	All	−0.686	.002	4	view →
UCEC	All	All	+1.279	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MAPK15–COAD

Open the COAD breakdown →