MAP9

Across TCGA cell cohorts, MAP9 mutation is significantly associated with the RNA expression of many other genes, with 997 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP9-associated genes across cancer lineages are OR5V1, ACER1, and KSR2. Each is linked with MAP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP9-to-partner and partner-to-MAP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5V1 grouped by MAP9-low versus MAP9-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP9→partner) and Y-score (partner→MAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR5V1 →	+0.011	+4.562	<.001	<.001	3	2
LARGE_INTESTINE	ACER1 →	+0.071	+2.238	<.001	<.001	3	2
LARGE_INTESTINE	KSR2 →	+0.485	+2.628	<.001	.002	3	2
BLOOD_Lymphoma	KRTAP4-4 →	+0.032	+5.643	<.001	.002	3	1
SKIN	DAZ3 →	+0.575	+3.793	.001	.007	3	1
SKIN	DAZ2 →	+0.511	+3.707	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 997 associations by consensus.

OR5V1 by MAP9 expression — SKIN

Explore this box plot interactively →