MAP9

Across TCGA pan-cancer cohorts, MAP9 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MAP9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MAP9 RNA is repressed in tumor relative to normal tissue. In most cancer types MAP9 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where MAP9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAP9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	−1.242	<.001	11	view →
KICH	Male	IV	−3.256	<.001	10	view →
THCA	Male	II,III,IV	−0.998	<.001	7	view →
READ	Female	All	−1.858	<.001	2	view →
CHOL	All	All	+1.750	<.001	2	view →
UCEC	All	IV	−1.645	.028	2	view →
KIRP	Female	II,III,IV	+0.715	.033	2	view →
PRAD	All	All	+0.328	.019	2	view →
LUSC	All	All	−0.314	.020	2	view →
LUAD	All	III,IV	−0.400	.026	1	view →
LIHC	Female	All	+0.363	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MAP9–KIRC

Open the KIRC breakdown →