MAP7D3

Across TCGA cell cohorts, MAP7D3 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP7D3-associated genes across cancer lineages are OR1L3, GALR1, and SH3GL2. Each is linked with MAP7D3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP7D3-to-partner and partner-to-MAP7D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by MAP7D3-low versus MAP7D3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7D3→partner) and Y-score (partner→MAP7D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	3
SKIN	GALR1 →	+0.972	+5.022	<.001	.002	3	2
LARGE_INTESTINE	SH3GL2 →	+1.084	+3.252	.004	.009	3	1
LARGE_INTESTINE	STK11 →	+0.646	+3.215	.003	.009	3	1
LARGE_INTESTINE	TEX101 →	+0.193	+3.502	<.001	.004	3	1
LARGE_INTESTINE	MRO →	+0.239	+3.392	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

OR1L3 by MAP7D3 expression — SKIN

Explore this box plot interactively →