MAP6D1

Across TCGA patient cohorts, MAP6D1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP6D1-associated genes across cancer lineages are NUTF2P8, RNA5SP405, and RNA5SP260. Each is linked with MAP6D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP6D1-to-partner and partner-to-MAP6D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUTF2P8 grouped by MAP6D1-low versus MAP6D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP6D1→partner) and Y-score (partner→MAP6D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUTF2P8 →	+0.153	+3.246	<.001	.008	3	1
UCEC	RNA5SP405 →	+0.442	+3.997	<.001	.009	3	1
UCEC	RNA5SP260 →	+0.640	+3.951	.007	.002	3	1
UCEC	RNU6-391P →	+0.448	+4.290	<.001	.001	3	1
UCEC	RNU6-1318P →	+0.569	+3.621	<.001	.004	3	1
UCEC	KLRC3 →	+0.170	+3.080	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

NUTF2P8 by MAP6D1 expression — UCEC

Explore this box plot interactively →