MAP6

Across TCGA cell cohorts, MAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,771 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MAP6-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with MAP6 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAP6-to-partner and partner-to-MAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by MAP6-low versus MAP6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP6→partner) and Y-score (partner→MAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.175	+1.015	<.001	.003	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.157	+1.015	<.001	.003	3	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.176	+1.015	<.001	.003	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.157	+0.947	<.001	.006	3	11
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.106	+2.531	<.001	<.001	3	11
OESOPHAGUS	Regulation of RNA splicing →	+0.094	+0.970	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,771 associations by consensus.

Negative regulation of myoblast fusion by MAP6 expression — OESOPHAGUS

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