MAP4K5

Across TCGA patient cohorts, MAP4K5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,097 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MAP4K5-associated proteins across cancer lineages are SEC23B, CDC42BPB, and PYCARD. Each is linked with MAP4K5 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAP4K5-to-partner and partner-to-MAP4K5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K5 versus SEC23B in OV, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K5→partner) and Y-score (partner→MAP4K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC23B →	-0.368	-0.692	<.001	.001	3	8
BRCA	CDC42BPB →	+0.262	+0.476	<.001	.001	2	8
CCRCC	PYCARD →	-0.503	-0.336	<.001	<.001	3	6
GBM	TNFAIP8 →	-0.510	-0.366	<.001	<.001	3	6
GBM	ARHGAP30 →	-0.405	-0.467	.004	<.001	3	6
LSCC	SUPT16H →	+0.348	+0.400	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,097 associations by consensus.

MAP4K5 vs SEC23B — OV

Explore this scatter interactively →