MAP4K4

Across TCGA cell cohorts, MAP4K4 RNA expression is significantly associated with the RNA expression of many other genes, with 13,032 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP4K4-associated genes across cancer lineages are RBFOX2, ASAP1, and CKAP2L. Each is linked with MAP4K4 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAP4K4-to-partner and partner-to-MAP4K4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K4 versus RBFOX2 in BREAST, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K4→partner) and Y-score (partner→MAP4K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RBFOX2 →	+1.515	+2.562	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	ASAP1 →	+1.632	+1.520	<.001	<.001	3	14
STOMACH	CKAP2L →	+1.272	+1.432	.002	<.001	3	13
BREAST	GATAD2A →	+1.088	+1.995	<.001	<.001	3	12
LARGE_INTESTINE	PRR11 →	+1.332	+1.592	<.001	<.001	3	12
URINARY_TRACT	SMURF2 →	+2.004	+1.345	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,032 associations by consensus.

MAP4K4 vs RBFOX2 — BREAST

Explore this scatter interactively →