MAP4K3

Across TCGA patient cohorts, MAP4K3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,498 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP4K3-associated proteins across cancer lineages are TNFAIP8, PTPRC, and SPN_S368. Each is linked with MAP4K3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP4K3-to-partner and partner-to-MAP4K3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K3 versus TNFAIP8 in GBM, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K3→partner) and Y-score (partner→MAP4K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TNFAIP8 →	-0.574	-0.411	<.001	<.001	3	6
PDAC	PTPRC →	-0.608	-0.410	<.001	<.001	3	6
LSCC	SPN_S368 →	-0.751	-0.434	<.001	<.001	3	6
GBM	FKBP15 →	-0.259	-0.408	<.001	<.001	3	6
GBM	CTBP2 →	+0.301	+0.399	<.001	<.001	3	6
HNSC	LCLAT1 →	+0.501	+1.009	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,498 associations by consensus.

MAP4K3 vs TNFAIP8 — GBM

Explore this scatter interactively →